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deskgamePicking a winner is difficult because the Fighting Irish and Nittany Lions have left no doubt in their CFP victories. If you’re looking for a team to back, consider my expert betting picks for Notre Dame versus Penn State. deskgameThe Rams enter TNF off a big home win in Week 14 over Josh Allen and the Bills. LA is a game behind Seattle. The Niners beat the skidding Bears at home and are two games behind Seattle. deskgameYou might want to place a futures bet on the Bills now, though, before the odds possibly shorten even more. Buffalo faces San Francisco next, and a win over the 49ers should at least lead to another slight odds move. deskgameHead coach Brent Venables is defensive-minded and should have a solid plan of attack against the triple option. Even with a downsized roster, Oklahoma still has more talent on its sideline. The final score will come down to how the fresh faces perform and how quickly the defense adjusts to an unfamiliar scheme.